GNE-7883
TAC04260
2648450-42-2
98%+
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Description

GNE-7883 (GNE7883) is a potent, reversible, allosteric inhibitor of the YAP1-TEAD interaction.
The potent inhibition of pan-TEAD lipidation with GNE-7883 translated well to the disruption of YAP1 binding to each of the four TEAD isoforms by the YAP1 HTRF assay.

Product Info

Cas No. 2648450-42-2
Solubility DMSO : 125 mg/mL (279.06 mM; ultrasonic and warming and heat to 60°C)
Appearance Solid powder.Please contact us for more accurate information.

Shipping and Storage

Store Temp Room temperature in continental US; may vary elsewhere.
Ship Temp Powder:3 years -20°C。In solvent:1 years -80°C

References

1. Jeffrey K Holden, et al. Cell Rep. 2020 Jun 23;31(12):107809.